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Did you know certain medications can interact with everyday food and drink? We asked VP of Pharmacy Services Adam Porath how to take these important medications safely. One in five Americans between the ages of 40 and 75 are currently taking a statin drug to reduce their cholesterol level or to prevent atherosclerosis (hardening of the arteries). Many others also take anticoagulants (blood thinners) to prevent blood clots from forming, which can increase the risk of stroke. Adam Porath, VP of Pharmacy Services at Renown Health, explains how to safely take these medications. What is a statin? A statin is a drug that can lower cholesterol by helping your body absorb cholesterol or by blocking a substance your body needs to make it. The American Heart Association cites a global study reporting the benefit of statins to help reduce heart attacks and strokes. Common statins include atorvastatin (Lipitor), pravastatin (Pravachol), rosuvastatin (Crestor) and simvastatin (Zocor). Which foods or drinks should be avoided while taking statin drugs? Grapefruit juice is the only food or drink that has a direct interaction with statins. Statins do not directly interact with any food but people taking statins should moderate their intake of saturated fats to help lower their LDL cholesterol and overall risk of cardiovascular disease. What is a blood thinning drug? Blood thinning drugs, such as warfarin, rivaroxaban (Xarelto), apixiban (Eliquis), dabigatran (Pradaxa) and edoxaban (Savaysa), are used to prevent stroke. Which foods or drugs should be avoided while taking blood thinning drugs? If taking warfarin, alcohol and cranberries (including juice) should be avoided. Patients taking warfarin should be aware of foods that contain Vitamin K (green leafy vegetables) and try to maintain a consistent diet of these foods. Warfarin interacts with many over the counter and prescription medications. Patients should consult a pharmacist when starting, stopping, or changing doses of any medication when taking warfarin. Also, patients taking any blood thinning medication should avoid over-the-counter pain relievers (i.e. aspirin, ibuprofen, etc.) How do I know whether to take my medication with food or not? Consulting with a pharmacist is the best resource to determine if a medication should be taken with or without food. In general, all statins and blood thinners can be taken with or without food. The only exception is Xarelto (rivaroxaban), which should be taken with the largest meal of the day If you are a Renown patient you can also review your prescriptions online, request a refill or ask a question via MyChart. With MyChart, you can access all your healthcare information securely 24/7.

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What exactly is the relationship between genetics and disease? Powered by Renown Health, the Healthy Nevada Project is one of the most visible genomic studies in the United States. They are recruiting participants here in northern Nevada to understand the relationship between genetics and nonalcoholic liver disease. Joseph Grzymski, Principal Investigator at the Healthy Nevada Project and Chief Scientific Officer at Renown Health, shares why this study is so important and who should take part. Many people are aware that heavy drinking can lead to liver disease. Yet they are unaware that other types of liver disease are not caused by alcohol consumption. These types of liver disease are more difficult to diagnose but are equally dangerous. What is NASH? A build-up of fat causes nonalcoholic Fatty Liver Disease (NAFLD) in the liver. The most dangerous form is called Nonalcoholic Steatohepatitis (NASH). It causes inflammation and damages liver cells, leading to fibrosis, scarring of the liver, and decreased liver function. If NASH goes untreated, irreversible liver damage can occur, leading to cirrhosis, cancer, or liver failure. These conditions can be fatal. What’s most concerning about NASH is that the symptoms don’t typically cause pain and aren’t noticeable. The good news is that a new local study is raising awareness about this disease by recruiting at-risk people for NASH. Am I at risk for developing NASH? The following factors put you at risk: Obesity Type 2 diabetes Metabolic syndrome High blood lipids, such as cholesterol and triglycerides Does having a family member with nonalcoholic liver disease increase my risk? We do not know a lot about inheriting NASH, although a lot risk factors run in families. One goal of this study is to better understand the genetic component of NASH. There are certainly other risks too, such as environmental and behavioral risk factors. However, we don’t yet have a good grasp on how these impact NASH risk. How is NASH diagnosed? Diagnosis is traditionally done with either a liver ultrasound or biopsy. However, both procedures are expensive and the invasive biopsy has risks. Therefore doctors often use risk factors or less invasive blood tests for diagnosis. This NASH study will include a new blood test called the enhanced liver function (ELF) test. Doctors and researchers have data suggesting that the ELF test is a better diagnostic test for NASH risk. Conducting this cutting-edge test with study participants allows them to share results with their doctors to ensure the best care. What can I do to reduce my NASH risk? Limiting exposure to the risk factors of NASH often lowers risk. Eating a healthy diet, maintaining a recommended weight and exercising regularly can proactively lower your risk.

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Colorectal cancer is the number two cancer killer in Nevada, only second to lung cancer, yet it is also one of the most preventable. Still, in 2020, 20.7% of Nevadans said they had never been screened for this deadly disease, according to the Nevada Cancer Coalition. At the start of the COVID-19 pandemic, unfortunately many healthcare services were halted, including colorectal cancer screenings. Those delays in screenings can lead to delays in diagnoses of colorectal cancer, resulting in poorer outcomes. Per the American Cancer Society, if colorectal cancer can be found early the relative 5-year survival rate is approximately 90%. Screening is key, and it is important to engage in preventative care. Even if you have no personal or family history of colorectal cancer, ask your doctor about colorectal risk factors and when to start screening, and if you’re up to date on your screenings, talk to loved ones and make sure they are too. According to the American Cancer Society, most colorectal cancer cases are found in those without a family history. This month let us help raise awareness for colorectal cancer and the importance of routine, life-saving screenings. To learn more, we spoke to Renown Health oncology nurse Christina Alsop, APRN. What is Colorectal Cancer Colorectal cancer is a disease in which the cells in the colon or rectum grow out of control. It usually forms from precancerous polyps, or abnormal growths, in the colon or rectum, which can become malignant without presenting any symptoms. How do Screenings Work Screening tests like stool tests, colonoscopies and others can detect these precancerous polyps, so they can be removed by a physician before turning into cancer. Screening tests can also find colorectal cancer early, resulting in better treatment outcomes. As of 2021, the U.S. Preventative Services Task Force recommends adults begin colorectal cancer screenings beginning at age 45, through 75. Screening methods include a blood stool test, which needs to take place every year or a colonoscopy, which takes place every 5-10 years. Healthy Habits Can Help Stave Off Risk Routine screenings are the only way to determine colorectal health, yet some healthy habits may reduce your risk for colorectal cancer. These factors include maintaining a healthy weight, being physically active, eating a diet rich in fresh fruits, vegetables and whole grains, limiting alcohol intake and not smoking.

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It doesn’t take long to feel at ease when you sit down with Michael and Lorraine Henson. They are the kind of people you immediately know you can count on and want to be friends with. They have had more than their fair share of hard knocks and yet they still maintain an air of warmth and gratitude. That sense of gratitude towards Renown and connection to this community is what led them to make a generous gift in their family trust to Renown Health Foundation. Home Means Nevada Michael and Lorraine met as students at the University of Nevada, Reno (UNR) and they’ve been together ever since. Lorraine moved from Las Vegas to attend UNR and never left. They have deep roots in Reno and deep roots with Renown going back to its Washoe Medical Center (Washoe Med) days. As Michael put it, he is “Reno born and Reno proud.” Michael’s mother was born at Washoe Med in 1937, but it was his personal experiences with Renown that formed his bond with the organization. When Michael was a teenager, his brother was diagnosed with brain cancer. He was treated over the course of the next six years at Renown before passing away at the tragically young age of 24. The impact on his family was life altering. Michael is an Eagle Scout and turned down a spot at the Air Force Academy to stay close and be with his brother. Renown provided support to Michael and his family during this incredibly difficult time as well as other times such as when his father was in hospice and when Lorraine had a health scare. The Ties That Bind A few years after his brother’s death, Michael joined the Renown team and has now been an employee for 31 years! Lorraine too has many connections to Renown. She was an employee for several years, volunteers for Renown Children’s Hospital and is a grateful patient. Making Their Mark Through Renown’s employee giving program Michael and Lorraine have given over $6,500 to support Renown’s mission to make a genuine difference in the health and well-being of the people and communities we serve. “These two are a wonderful example of how small gifts over time really add up and their decision to include Renown Health Foundation in their estate plans can be an inspiration to us all this month in particular, as August is Make a Will Month,” said Greg Walaitis, Chief Development Officer at Renown Health Foundation. “Michael and Lorraine have supported Renown in every way imaginable over the years, including with their time, their talents and their treasure. It is an honor to have them as part of our Renown family.” We are also incredibly grateful to have Michael and Lorraine as members of the Renown Legacy Society, which recognizes donors who have provided for Renown Health Foundation in their estate plans, and we look forward to celebrating them at the Inaugural Renown Legacy Society Celebration taking place on August 30.

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Since the COVID-19 pandemic, more people are working from home than ever before, leading to a rise in digital screen time. Between spending eight or more hours staring at a computer screen, and some downtime hours spent looking at a smartphone or watching TV, it’s almost inevitable to feel some adverse effects at the end of a day. Blue Light Effects vs. Digital Eye Strain Blue light is all around us, and the most natural source comes primarily from sunlight. Other forms of blue light are artificial and emitted by digital screens including LED TVs, smartphones, tablets and computers. Surprisingly enough, research shows blue light can actually have health benefits such as promoting alertness, boosting memory and cognitive function, elevating mood and regulating circadian rhythm. However, studies indicate that an excess in blue light exposure can lead to depletion of melatonin production, a hormone that regulates our sleep cycles. In today’s eyewear industry, blue light glasses are one of the more popular items purchased by consumers. Companies who sell the glasses claim they help with reducing or eliminating digital eye strain, while also increasing natural melatonin secretion to get a good night’s sleep. Other than their slight yellow tint to filter out blue light, they mostly look like regular glasses and come in many different stylish frames. You can find blue light glasses through various eyewear retailers. Most adults have experienced digital eye strain. Common symptoms of digital eye strain include headaches, blurred vision, irritated eyes, and fatigue. Many believe that digital eye strain is caused by overexposure to blue light, but medical vision experts say that is not the case. “Digital eye strain is related to how we use our digital devices, not the blue light coming out of them,” says Mitchell Strominger, MD, a neuro and pediatric ophthalmologist with Renown Health. Do Blue Light Glasses Even Work? Since blue light glasses aren’t medically proven to help with digital eye strain, you’re probably wondering if they’re even worth using. “If you’re one to binge a TV show or scroll though social media before bedtime, the blue light from those digital screens can disrupt your circadian rhythm and cause you to lose sleep, which can ultimately lead to other adverse health effects,” says Dr. Strominger. “While more research is still needed, some studies have shown that blue light glasses may prevent melatonin suppression and increase quality of sleep. There is no harm in trying them out and seeing if they work for you.” As for preventing digital eye strain, Dr. Strominger shared several helpful tips: Try using the 20-20-20 rule, which entails looking away from your screen and looking at an object 20 feet away for at least 20 seconds. Sit at an arm’s length (about 25 inches) away from your screen. Adjust the brightness and contrast of your screen, especially before bedtime. There is a night mode setting on most smart phones you can use. Reduce your screen time whenever you can and give your eyes a break.

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With more than 29 million adult Americans having high cholesterol, it’s important to know the facts. We asked Jayson Morgan, MD, a cardiologist with Renown Institute for Heart and Vascular Health, explains the numbers, the risk factors and how to maintain healthy levels. What is cholesterol? There are two types: Low-density lipoprotein (LDL) cholesterol, also known as the “bad” variety, because it can eventually build up within the walls of your blood vessels and narrow the passageways. High-density lipoprotein (HDL), also known as the “good” variety, because it helps remove other forms of cholesterol from the bloodstream. In adults, total cholesterol is considered high if it is more than 200 mg/dL. If the total is more than 200 or if high-density lipoprotein (HDL) levels are less than 40, your heart and brain may not be getting as much oxygen-rich blood as they need. This puts you at greater risk of heart attack and stroke. HDL levels greater than 60 mg/dL can actually lower your risk. What are the risk factors for high levels? Diet high in saturated fat Excess body weight Lack of exercise Smoking Family history Age (as people age, they are more prone to high levels) How often should someone get their numbers checked, and what kind of test is done? The American Heart Association recommends all adults age 20 or older have their cholesterol checked every four to six years. Those with cardiovascular disease or who are at higher risk of it may need their levels and other risk factors assessed more often. Your primary care provider can perform the test, along with assessing your other risk factors to help determine a treatment plan if necessary. The test will likely be one you will need to fast for, meaning no food, beverages or medications for around nine to 12 hours. Your healthcare provider will let you know if, and for how long, to fast. A simple blood test is all that’s needed to get your levels. What are some ways to lower “bad” cholesterol and raise “good” cholesterol? To achieve healthier levels, people should: Eat a heart-healthy diet: Choose healthier fats, eliminate trans fats, eat foods rich in omega-3 fatty acids and increase soluble fiber. Increase physical activity: Exercise on most days of the week. Quit smoking: If you smoke, it’s time to stop. Quitting smoking will improve HDL “good” cholesterol levels. Lose weight: Losing as little as five to 10 percent of your weight can improve cholesterol levels. Drink alcohol only in moderation. And finally, if lifestyle changes aren’t enough, your care provider might recommend medication to help lower your numbers. Renown Institute for Heart & Vascular Health For optimal heart health, the American Heart Association encourages you to “Know Your Numbers” which include: blood pressure, body mass index (BMI), cholesterol and fasting blood sugar, by scheduling a visit with your doctor. These numbers are critical in assessing your current risk for heart disease and stroke. Find a Cardiologist

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Alzheimer’s disease is not normal forgetfulness as we age. Instead, it is a specific form of mental decline. And according to the Alzheimer’s Association it accounts for nearly 80 percent all dementia cases. Natasa Dragicevic, MD, PhD., behavioral neurologist and Alzheimer’s disease specialist with Renown Institute for Neurosciences, weighs in on diagnosing it and the importance of early medical action. How to Diagnose Alzheimer’s Disease In general, the signs of Alzheimer’s disease occur slowly, getting worse over time. For example, forgetfulness is a daily search – for shoes, keys and other misplaced items. Not only is memory affected, but also speech patterns and behavior. There is no single test for Alzheimer’s disease. “Specifically, a neurologist should be the one to diagnose Alzheimer’s disease given differences in presentation,” clarifies Dr. Dragicevic. “And ideally a behavioral neurologist (Alzheimer’s sub-specialist) will be managing the treatment,” she adds. Brain Imaging Diagnosing Alzheimer’s disease involves multiple approaches and medical providers. In short, medical history is reviewed along with a physical exam, lab tests and other diagnostic testing. “A medical workup includes a variety of tests. These include MRI and other brain imaging, as well as neurological and psychological testing. Furthermore, a lumbar puncture is performed to look for markers of the disease,” she states. What Causes Alzheimer’s disease? Although no one knows the cause, researchers think many factors play a role. Uncontrollable risk factors include your genetics and having a family member with the disease. However, the controllable risk factors include: reducing the risk of head injury and keeping your heart healthy. It’s important to realize that high blood pressure, high cholesterol, stroke and diabetes play a role in brain health. Blood loss to the brain causes vascular dementia, leading to long-term blood vessel damage. Symptoms of Alzheimer’s disease Generally speaking, the signs of this disease differ in each person. Yet noticeable behaviors include: • Losing the way to familiar places • Forgetting to pay bills • Trouble finding the right words when talking • Repeating questions • General confusion • Social withdrawal Alzheimer’s Disease – Benefits of Early Diagnosis Equally important, spotting Alzheimer’s disease early allows more time to benefit from medications and possible clinical trials. Likewise, nutrition and exercise changes can be made, increasing blood flow to the body, and perhaps delaying symptoms. Early diagnosis also allows for personal health decisions and quality-of-life conversations to take place.   According to the Alzheimer’s Association, these benefits include: 1. Medical advantage 2. Emotional and social comfort 3. Time to plan ahead 4. Cost savings A Brain Supporting Lifestyle “At the present time, treatment is limited,” explains Dr. Dragicevic. “Usually Alzheimer’s is a progressive ongoing disease – any management at this time is purely symptomatic.” However, she states the following lifestyle changes can help support brain health: • New hobbies such as painting, pottery, music classes or learning a new language • Crosswords, puzzles and playing games, such as Scrabble • Brain challenging mobile apps, such as Luminosity • 30-45 minutes of mild to moderate physical activity per day, such as walking • Eating a Mediterranean diet (primarily plant based foods)

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Despite the challenges of a pandemic, the Renown Rehabilitation Hospital continues to help their patients thrive outside of the hospital walls. On July 31, 2021, they hosted the first-ever Renown Alumni Sports Extravaganza, or RASE, a day focused on adaptive sports for all abilities. “Sports and recreation have a unique way of breaking down emotional barriers,” states Jared Worchel, DO, MS. The alumni used their skills on a climbing wall, Frisbee golf, archery, an obstacle course and bag toss. Over 20 people spent the day cruising the first adaptive mountain biking trail in the Tahoe region. “Having old friends meet up and seeing new friendships form had to be the highlight of the weekend,” says Shaun Stewart Certified Therapeutic Recreation Specialist (CTRS) with Renown Rehabilitation Hospital. “RASE was a great way to learn new methods to improve outdoor recreation engagement from both participants and the many programs involved.” Dr. Worchel agrees, “The smiles really make it worth it, and we even saw several touching moments with tears of joy when participants completed a task and finally felt like they were getting past their injury, mentally, after years of being so focused on recovery.” Adaptive Climbing and Camping One touching moment came on the adaptive climbing wall. Cassie Firchau, an occupational therapist at Renown, recalls a rehab alumni who had never been on a climbing wall (pre or post injury) conquering the wall. “Everyone was cheering him on. I was impressed with how he used the ascending pull up bar to get up the wall,” she remembers. Mark Wellman, the founder of No Limits, provided the climbing wall. “I had heard of Mark, but I had no idea that he climbed El Capitan only a few years after his spinal cord injury,” says Cassie. “Having him at the event was a great opportunity to learn how to stay active and enjoy the things you love, no matter the circumstance.” After dark, the event continued with a DJ spinning hits followed by overnight camping. That evening Shaun Stewart had the chance to talk to one of the alumni. “He spoke on how he was nervous about camping and how it would go in a new campground. He said that he was happy for an opportunity to practice with our group prior to going out on his own,” remarks Stewart. “Knowing that this event can help create opportunities even outside our events is great to know.” Adaptive camping activities allow all abilities to not only enjoy nature, but also connect. “We also saw a lot of interaction between the participants themselves, sharing their journeys with each other during the down times which was possible with the extended format,” explains Dr. Worchel. “Overall it was an overwhelming success and we are already looking forward to next year.” Northern Nevada's Adaptive Sports Community Not only did the Renown Rehab alumni come together at RASE, but so did the greater northern Nevada community. Along with the hard work of the Renown Rehabilitation employees, the City of Reno Adaptive and Inclusion Programs, Wasting Arrows, Disable Sports Eastern Sierra, No Limits, and High Fives Foundation, provided support and equipment for the alumni. “It was so great to see multiple groups, volunteers and non-profits collaborating to support alumni participants to live life to the fullest, and to experience outdoor recreation in such a dynamic way,” states Josh Patterson, Supervisor of Rehab Therapy Services at Renown Health. "The City of Reno is so grateful for this sponsorship to bring together new and old Renown alumni to learn and encourage each other. There were many firsts this weekend, and we look forward to future participation in City of Reno Adaptive programs,” says April Wolfe, CTRS, City of Reno Parks and Recreation. For more information on future alumni adaptive events, please email: shaun.stewart@renown.org.

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Over the past year, the safety of healthcare providers has received more public attention than ever before. Throughout the COVID-19 pandemic – and particularly in the early days – the public learned about the vital role of personal protective equipment (PPE) and other important processes that keep healthcare workers safe and healthy. However, people may be surprised to learn that germs and viruses are just one of the many risks that healthcare professionals face every day. Many people are fortunate enough not to have to worry for their physical and mental well-being when they go to work. Unfortunately, this is not the case for countless healthcare workers across the nation, for whom workplace violence is a daily concern. According to the American Hospital Association, healthcare workers are four times more likely to experience serious workplace violence than people in other industries. This is particularly troubling knowing that healthcare workers have dedicated their careers to serving others, putting their communities first- day in and day out. What is Considered Workplace Violence? The World Health Organization (WHO) defines workplace violence as, “Incidents where staff are abused, threatened, or assaulted in circumstances related to their work, including commuting to and from work, involving an explicit or implicit challenge to their safety, well-being, or health.” WHO considers both physical and psychological harm, including attacks, verbal abuse, bullying, and both sexual and racial harassment, to be workplace violence. Responding to the Challenge of Workplace Violence At Renown Health, we have no tolerance for abuse against our employees. As an organization, we have several systems in place to support and protect our staff. During staff orientation, we provide classes to prepare employees to prevent and de-escalate verbal or physical abuse. We also offer ongoing education to train our staff to respond to violent situations. If an incident does occur, our Violence Prevention Task Force reviews incidents and ensures the impacted employees receive resources and counseling to help them process what has occurred. We are among the first in the nation to have instituted a Zero Tolerance policy on workplace violence. This policy is in place to let our employees know that we have their backs in preventing workforce violence and we will address it assertively if the environment becomes unsafe. As a leader, I am continually impressed by our team’s desire and ability to support one another. However, I know that it is my responsibility to protect our team. No one should have to face harassment or abuse – in any form – in his or her workplace. I believe so much in this cause that I volunteer as Chair of the American Hospital Association’s Hospitals Against Violence steering committee, which works to understand the causes behind violence against healthcare workers and develops tools and processes to prevent these incidents from occurring. Violence was already a concern facing health care organization leaders prior to the COVID-19 pandemic. Now, the ongoing health crisis has elevated tensions. Health care is an industry like no other, with our most precious resource being our employees. As a community, as patients and family members, we have an obligation to ensure that all healthcare workers are safe while they go about their work. This starts with understanding, communication and unequivocal support for the profession. This month we launched the Be Kind campaign across Renown, a reminder to all of the importance of values like patience, kindness and gratitude. If you would like to join us in recognizing a healthcare hero, please submit your thoughts here. Thank you for working with us, and all healthcare providers, to create and maintain places of health and healing for all – and for kindly caring for those who care for you.

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September is National Healthy Aging Month, which is described by Healthy Aging Magazine as a “month designed to focus national attention on the positive aspects of growing older.”   What does healthy aging mean to you? If you're like most people, you're looking forward to removing the negative from your life – negative energy, thoughts, people and activities that don't contribute to your best life.   While we remain focused on ridding ourselves of the negatives, we can forget about ways to strengthen the positive parts of our lives. Dr. Shruti Basho, a family medicine physician at Renown Health’s senior-focused medical group, provides us with five positive behaviors to focus on to improve happiness and life satisfaction.  Healthy Aging in 5 Easy Steps  Connect – Humans are naturally social creatures! Build connections with friends, family, colleagues and neighbors. Strong interpersonal connections help enrich your life with new experiences and opportunities. Having a support system to call upon in both times of need and times of celebration is priceless, especially as you age. Forming these bonds helps you stay healthier and happier well into your aging journey. Joining the Sterling Silver Club is a great place to meet more people in the community who want to live a healthy, fulfilled life just like you. Be Active – Regular exercise, particularly as you grow older, is vital to increase and maintain your endurance, strength and balance. But exercise doesn’t have to be a chore! Pick a physical activity that you enjoy – whether it be enjoying a nature walk, taking a power weightlifting class or anything in between. Being active will also help you build strong connections with others. If you need a workout buddy in your neighborhood, Nextdoor is a great resource to find people who live right around the block from you and may be looking for their next exercise partner.   Take Notice – Curiosity and mindfulness can be an impactful motivator in positive cognition and behavior as you age. Like a child, see the wonder and beauty of the world. Notice the things around you – the weather, the landscape, the mood and the feelings of people. According to Harvard Medical School, changes in the aging brain "enable us to become better at detecting relationships between diverse sources of information, capturing the big picture, and understanding the global implications of specific issues.” By taking notice, it’s easier to learn to appreciate the things that matter.  Keep Learning – Engaging with lifelong learning is one of the best ways to keep your mind active. Keep trying something new! Challenges keep you on your toes and increase your confidence and excitement in your day. Don’t know where to start? EPIC (Educational Programs Inspiring the Community) offers a diverse personal enrichment and professional development curriculum at Truckee Meadows Community College ranging from art classes to accelerated training certificate courses.  Give – Be generous with your time, your knowledge and your talents by giving to friends, family and the community when you have the capacity. Lending yourself to others doesn’t have to be taxing – saying thank you and even just giving someone a smile can change the course of someone’s day. If you’re looking for a hands-on way to give back, Nevada Volunteers is a great place to find volunteer opportunities near you. Renown Health is also always looking for volunteers who are passionate about making an unforgettable difference to the people and communities we serve.   Practice these five tips to improve happiness and quality of life at any age.

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